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Evidence-Based Supplement Research

Evidence-Based Supplement Research

red yeast rice and Reduced Triglyceride Levels

Doses used in studies

mg/day: 200–4,800 (median 2,500, IQR 200–4,800) — 1 study

Time to effect

Median: 2.8 months · IQR 2.8 months–2.8 months · Range 2.8 months–2.8 months — Reported in 1 of 2 studies

Safety in these studies

Overall tolerabilityReported
did not increase the risk of adverse events in patients with hyperlipidemia
from: Red Yeast Rice for Hyperlipidemia: A Meta-Analysis of 15 High-Quality Randomized Controlle

2 of 2 papers

Impact of red yeast rice supplementation on lipid profile: a systematic review and meta-analysis of randomized-controlled trials.
- 2022-10-25
- Meta-Analysis
- Expert review of clinical pharmacology 16(1)
- - Parisa Rahmani
  - Ebru Melekoglu
  - Sogand Tavakoli
  - Nasser Malekpour Alamdari
  - Pejman Rohani
  - Mohammad Hassan Sohouli
- PubMed: 36259545
- DOI: 10.1080/17512433.2023.2138342
4 Insights on
- Reduced Triglyceride Levels
- High evidence
- Clinical
significant effectiveness in lowering TG (WMD: -23.36 mg/dl, 95% CI: -31.30, -15.43, P < 0.001)
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Dose
less than 1200 mg
Red Yeast Rice for Hyperlipidemia: A Meta-Analysis of 15 High-Quality Randomized Controlled Trials.
- 2022-01-17
- Review · n = 12
- Frontiers in pharmacology 12
- - Pengfan Li
  - Qi Wang
  - Kanjun Chen
  - Shihui Zou
  - Shi Shu
  - Chanchan Lu
  - Shiyun Wang
  - Yunqin Jiang
  - Chunxiang Fan
  - Yue Luo
- PubMed: 35111069
- DOI: 10.3389/fphar.2021.819482
5 Insights on
- Reduced Triglyceride Levels
- Low evidence
- Clinical
RYR effectively synergized nutraceutical to further reduce ... TG (MD, -26.32; 95% CI, -34.05 to -18.59; p < 0.00001)
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Dose
200-4800 mg daily (combined with nutraceutical)