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Evidence-Based Supplement Research
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saccharomyces boulardii and Reduced Duration of Diarrhea

Research synthesisModerate evidenceSmall effect4 studies · 3 beneficial · 1 neutral · 0 harmful

Across 4 studies, 3 reported beneficial effects of Saccharomyces boulardii on reducing diarrhea duration, predominantly with small effect sizes. The most studied population is children (especially under 5 with acute gastroenteritis), and no consistent dose range was reported across studies. One meta-analysis showed a neutral result, adding some uncertainty.

  • Studied populations: children under 5 with acute gastroenteritis or non-bloody diarrhea

Caveats: Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Evidence base is small (only 4 studies) — conclusions should be considered preliminary. The only meta-analysis included found a neutral effect (non-significant), which tempers confidence in the beneficial direction. No consistent dose or form data were extracted, limiting practical application.

Generated Jun 20, 2026
Safety in these studies
4 of 4 papers
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