Best Supplements for Reduced Duration of Diarrhea
Ranked by research evidence. Compare 29 supplements across 40 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Moderate evidence5 studies
Across 5 studies, all reported beneficial effects of Lactobacillus reuteri DSM 17938 on reducing diarrhea duration, with effect sizes ranging from small to large (predominantly moderate-to-large). Statistically significant findings were observed in 4 out of 5 studies. The most-studied dose was approximately 1-2 × 10^8 CFU/day, primarily in children with acute diarrhea or at risk for antibiotic-associated diarrhea.
Dose: 1 × 10^8 to 2 × 10^8 CFU/dayProduct matchBioGaia — Kids, Immune Active with L. Reuteri + Vitamin D, Orange· $26.99 · ★4.8 (510) - Moderate evidence4 studies
Across 4 studies, 3 reported beneficial effects on reducing diarrhea duration, with effect sizes ranging from small to moderate. Evidence primarily comes from pediatric populations with acute diarrhea.
- Low evidence3 studies
Across 3 studies on Lactobacillus reuteri MAK02L14R (studied as DSM 17938) and reduced diarrhea duration, 2 reported beneficial effects and 1 found no significant difference. Effect sizes were mixed: one meta-analysis reported a small reduction (mean difference -0.87 days), while another reported a large reduction (-32 hours). The predominant population studied was children with acute gastroenteritis.
- ModerateLactobacillus reuteri DSM 17938Across 5 studies, all reported beneficial effects of Lactobacillus reuteri DSM 17938 on reducing diarrhea duration, with effect sizes ranging from small to large (predominantly moderate-to-large). Statistically significant findings were observed in 4 out of 5 studies. The most-studied dose was approximately 1-2 × 10^8 CFU/day, primarily in children with acute diarrhea or at risk for antibiotic-associated diarrhea. · Dose: 1 × 10^8 to 2 × 10^8 CFU/day5 beneficial5 studies
- Moderatesaccharomyces boulardiiAcross 4 studies, 3 reported beneficial effects on reducing diarrhea duration, with effect sizes ranging from small to moderate. Evidence primarily comes from pediatric populations with acute diarrhea.3 beneficial1 neutral4 studies
- LowLactobacillus reuteri MAK02L14RAcross 3 studies on Lactobacillus reuteri MAK02L14R (studied as DSM 17938) and reduced diarrhea duration, 2 reported beneficial effects and 1 found no significant difference. Effect sizes were mixed: one meta-analysis reported a small reduction (mean difference -0.87 days), while another reported a large reduction (-32 hours). The predominant population studied was children with acute gastroenteritis.2 beneficial1 neutral3 studies