L-Carnitine and Reduced Abdominal Pain

Doses used in studies

g/day: 2 (median 2, IQR 2–2) — 1 study

Time to effect

Median: 8 weeks · IQR 8 weeks–8 weeks · Range 8 weeks–8 weeks — Reported in 1 of 1 study

Safety in these studies

Overall tolerabilityReported
The abstract does not report any adverse events, side effects, or safety findings. It only reports efficacy/ biomarker outcomes (IGF-1, CK, myostatin, myogenin levels). No tolerability statement is made.
from: l-carnitine downregulate the muscle wasting effect of glucocorticoids in pemphigus patient

1 of 1 paper

l-carnitine downregulate the muscle wasting effect of glucocorticoids in pemphigus patient: A randomized double-blind placebo-controlled study.

2023-04
RCT
Physiological reports 11(8)
- Zeinab Noormohammadi
- Hana Arghavani
- Mohammadhasan Javanbakht
- Maryam Daneshpazhooh
- Mahmood Jalili

PubMed: 37078370
DOI: 10.14814/phy2.15657

6 Insights on

Reduced Abdominal Pain

High evidence
Clinical

Myogenin levels decreased in both LC and placebo groups but the decrease in the placebo group was significant (p = 0/008); it means LC prevent the myogenin decreasing trend in the LC group compared to placebo.

Effect: Neutral
Effect size: Small
Significant: No
Dose: 2 g/d