Best Supplements for Increased Serum Free Thyroxine Levels
Ranked by research evidence. Compare 7 supplements across 9 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Moderate evidence3 studies
Across 3 studies, 2 reported beneficial small-sized effects on increasing serum free thyroxine levels, with 1 neutral finding. Effects were predominantly small. Most studies involved clinical populations with autoimmune thyroid disease (Hashimoto thyroiditis, Graves-Basedow disease) and dosing around 200 μg/day. Effects typically observed at 8–12 weeks.
Dose: 200 μg per day
7 supplements
- ModerateSeleniumAcross 3 studies, 2 reported beneficial small-sized effects on increasing serum free thyroxine levels, with 1 neutral finding. Effects were predominantly small. Most studies involved clinical populations with autoimmune thyroid disease (Hashimoto thyroiditis, Graves-Basedow disease) and dosing around 200 μg/day. Effects typically observed at 8–12 weeks. · Dose: 200 μg per day2 beneficial1 neutral3 studies