Best Supplements for Reduced All-Cause Mortality
Ranked by research evidence. Compare 20 supplements across 27 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Moderate evidence3 studies
Across 3 studies, all reported beneficial effects of chili pepper consumption on reduced all-cause mortality. Effect sizes ranged from small to moderate; a 2023 meta-analysis (N=564,748) found a small but significant risk reduction (HR 0.87), while two other analyses showed moderate reductions (HR 0.77; RR 0.75). Doses were not consistently reported, but one study found benefit with intake >4 times per week. General adult populations were studied, primarily from observational cohorts.
20 supplements
- ModerateChili PepperAcross 3 studies, all reported beneficial effects of chili pepper consumption on reduced all-cause mortality. Effect sizes ranged from small to moderate; a 2023 meta-analysis (N=564,748) found a small but significant risk reduction (HR 0.87), while two other analyses showed moderate reductions (HR 0.77; RR 0.75). Doses were not consistently reported, but one study found benefit with intake >4 times per week. General adult populations were studied, primarily from observational cohorts.3 beneficial3 studies