Best Supplements for Reduced All-Cause Mortality
Ranked by research evidence. Compare 13 supplements across 17 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Low evidence3 studies
Across 3 studies, all reported beneficial effects on reduced all-cause mortality, with effect sizes ranging from small to moderate. The largest meta-analysis (N=564,748) found a small but significant risk reduction (HR 0.87, 95% CI: 0.85–0.90), while higher intake frequency (>4 times per week) was associated with a moderate reduction in Italian adults (HR 0.77, 95% CI: 0.66–0.90). Most evidence comes from observational studies in general adult populations; no specific dose or form was consistently reported across studies.
13 supplements
- LowChili PepperAcross 3 studies, all reported beneficial effects on reduced all-cause mortality, with effect sizes ranging from small to moderate. The largest meta-analysis (N=564,748) found a small but significant risk reduction (HR 0.87, 95% CI: 0.85–0.90), while higher intake frequency (>4 times per week) was associated with a moderate reduction in Italian adults (HR 0.77, 95% CI: 0.66–0.90). Most evidence comes from observational studies in general adult populations; no specific dose or form was consistently reported across studies.3 beneficial3 studies