Vitamin D and Reduced All-Cause Mortality

Doses used in studies

Safety in these studies

all-cause mortalityNo significant differenceSerious adverse eventrisk ratio (95% CI) of 0.95 (0.87-1.04)
This regimen showed no increase in all-cause mortality, with a risk ratio (95% CI) of 0.95 (0.87-1.04).
from: Effects of intermittent overload doses of oral vitamin D3 on serum 25(OH)D concentrations
fallsNo significant differencerisk ratios of 1.02 (0.98-1.05)
it did not significantly reduce the risks of falls and fractures, with risk ratios of 1.02 (0.98-1.05) and 0.95 (0.87-1.04) respectively.
from: Effects of intermittent overload doses of oral vitamin D3 on serum 25(OH)D concentrations
fracturesNo significant differenceSerious adverse eventrisk ratios ... 0.95 (0.87-1.04)
it did not significantly reduce the risks of falls and fractures, with risk ratios of 1.02 (0.98-1.05) and 0.95 (0.87-1.04) respectively.
from: Effects of intermittent overload doses of oral vitamin D3 on serum 25(OH)D concentrations
adverse eventsReported
The trial reported no adverse events in the moderate-dose vitamin D arm, but did not provide any information on adverse events in the placebo arm.
from: Oral vitamin D supplementation for adults with obesity undergoing bariatric surgery.
fallsReported
further research is needed to determine if this method would increase the incidence of falls. Therefore, it is not recommended at this stage due to the lack of demonstrated safety in additional relevant RCTs.
from: Effects of intermittent overload doses of oral vitamin D3 on serum 25(OH)D concentrations

2 of 2 papersPopulation:

Oral vitamin D supplementation for adults with obesity undergoing bariatric surgery.