Best Supplements for Reduced Bleeding on Probing (BOP)
Ranked by research evidence. Compare 28 supplements across 33 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Low evidence5 studies
Across 5 studies on Lactobacillus reuteri for reducing bleeding on probing (BOP), 3 reported beneficial effects (2 with moderate or large effect sizes) and 2 found neutral results. The most-studied dose range involved lozenges taken 1–2 times daily, and effects were typically observed in patients with periodontitis over durations of 3 weeks to 12 months, though median study duration was only about 101 days. 3 studies reached statistical significance, but the evidence is mixed in both direction and magnitude.
Dose: 1–2 lozenges per day
28 supplements
- LowLactobacillus reuteriAcross 5 studies on Lactobacillus reuteri for reducing bleeding on probing (BOP), 3 reported beneficial effects (2 with moderate or large effect sizes) and 2 found neutral results. The most-studied dose range involved lozenges taken 1–2 times daily, and effects were typically observed in patients with periodontitis over durations of 3 weeks to 12 months, though median study duration was only about 101 days. 3 studies reached statistical significance, but the evidence is mixed in both direction and magnitude. · Dose: 1–2 lozenges per day3 beneficial2 neutral5 studies