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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Best Supplements for Reduced Constipation

Ranked by research evidence. Compare 10 supplements across 12 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.

Top picks by evidence

  • Moderate evidence3 studies

    Across 3 studies, all 3 reported statistically significant beneficial effects of Saccharomyces boulardii on reducing constipation, with predominantly large effect sizes (risk ratios of 0.35–0.38). Evidence comes from meta-analyses of clinical populations undergoing Helicobacter pylori eradication therapy; no dose or form data were consistently reported, and study durations were not provided.

10 supplements
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