Best Supplements for Reduced Probing Depth
Ranked by research evidence. Compare 12 supplements across 17 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Low evidence3 studies
Across 3 studies, 1 reported beneficial effects (large effect size) on reduced probing depth, while 2 found neutral effects. The evidence is preliminary and mixed, with the lone beneficial study using 1×10⁹ CFU/day for 56 days in periodontitis or gingivitis patients, while two longer (180-day) studies in diabetic periodontitis patients showed no significant benefit over placebo. Median study duration was 180 days.
Dose: 1×10⁹ CFU/day
12 supplements
- LowLactobacillus reuteriAcross 3 studies, 1 reported beneficial effects (large effect size) on reduced probing depth, while 2 found neutral effects. The evidence is preliminary and mixed, with the lone beneficial study using 1×10⁹ CFU/day for 56 days in periodontitis or gingivitis patients, while two longer (180-day) studies in diabetic periodontitis patients showed no significant benefit over placebo. Median study duration was 180 days. · Dose: 1×10⁹ CFU/day1 beneficial2 neutral3 studies