Best Supplements for Reduced Thyroid Peroxidase Antibody Level
Ranked by research evidence. Compare 1 supplement across 4 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Moderate evidence4 studies
Across 4 studies, all reported beneficial effects of selenium supplementation on reducing thyroid peroxidase antibody (TPOAb) levels, with effect sizes ranging from small to large. The two highest-quality meta-analyses (total N ≈ 4,000) showed moderate-to-large reductions (SMD -0.46 to -0.96) in patients with Hashimoto thyroiditis. Effects were observed at 3–6 months; dose and form were not consistently reported.
1 supplement
- ModerateSeleniumAcross 4 studies, all reported beneficial effects of selenium supplementation on reducing thyroid peroxidase antibody (TPOAb) levels, with effect sizes ranging from small to large. The two highest-quality meta-analyses (total N ≈ 4,000) showed moderate-to-large reductions (SMD -0.46 to -0.96) in patients with Hashimoto thyroiditis. Effects were observed at 3–6 months; dose and form were not consistently reported.4 beneficial4 studies