Skip to main content
Evidence-Based Supplement Research
Evidence-Based Supplement Research
Pillser
Search
Sign UpLog In

Aloe Vera and Reduced Pain

Research synthesisLow evidenceMixed effect size3 studies · 2 beneficial · 1 neutral · 0 harmful

Across 3 studies, 2 reported beneficial effects (one small, one moderate) on pain reduction with aloe vera, while one meta-analysis found no significant difference. The evidence base is small and mixed, with effect sizes ranging from small to moderate. Studies focused on oral ulcer conditions (recurrent aphthous stomatitis and radiation-induced oral mucositis).

  • Studied populations: people with recurrent aphthous stomatitis (RAS) or radiation-induced oral mucositis

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. One meta-analysis found no statistically significant benefit, indicating inconsistency. Effect sizes varied from small to moderate across studies.

Generated Jul 9, 2026
Safety in these studies
3 of 3 papers
Back to top