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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Artichoke and Reduced Low-Density Lipoprotein Level

Research synthesisLow evidenceSmall effect3 studies · 3 beneficial · 0 neutral · 0 harmful

Artichoke supplementation shows moderate evidence for a small to moderate beneficial effect on reducing LDL-C levels, based on 3 studies. All 3 studies reported significant beneficial findings, with one meta-analysis reporting an average reduction of ~17.5 mg/dL. Effects were observed in clinical populations (bariatric surgery candidates and NAFLD patients) over a median study duration of 42 days, though dosing information was limited.

  • Studied populations: adults undergoing bariatric surgery, patients with non-alcoholic fatty liver disease (NAFLD)

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Dosing information was not clearly reported across most studies, limiting the ability to recommend a specific effective dose.

Generated May 13, 2026
Time to effect
Median: 6 weeks · IQR 6 weeks6 weeks · Range 6 weeks6 weeks — Reported in 1 of 3 studies
3 of 3 papers
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