Research synthesisModerate evidenceSmall effect4 studies · 4 beneficial · 0 neutral · 0 harmful
Across 4 studies, all reported beneficial effects of artichoke supplementation on reducing triglyceride levels, with three studies showing small effects and one showing a moderate effect. All four findings were statistically significant. The most-studied doses range from 600 to 1800 mg daily, and effects were observed in clinical populations such as those with non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome, with a median study duration of 72 days (approximately 10 weeks).
- Effective dose range: 600-1800 mg daily
- Studied populations: people with non-alcoholic fatty liver disease (NAFLD) and women with metabolic syndrome
Caveats: Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Most studies focused on specific clinical populations; generalizability to healthy individuals is unclear. Two studies did not report duration, and the median duration of 72 days suggests that effects may require at least 8 weeks of supplementation. Doses varied across studies, and the optimal dose remains to be established.
Generated Jun 15, 2026