Research synthesisModerate evidenceSmall effect4 studies · 4 beneficial · 0 neutral · 0 harmful
Across 4 studies, all reported beneficial effects on triglyceride levels, with predominantly small effect sizes. The most-studied doses range from 600 to 1800 mg/day of artichoke leaf extract, and effects were typically observed over 8–12 weeks in clinical populations with NAFLD or metabolic syndrome.
- Effective dose range: 600–1800 mg/day
- Studied populations: clinical populations with non-alcoholic fatty liver disease (NAFLD) or metabolic syndrome
Caveats: Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Most studies had small sample sizes (50–100 participants) and focused on specific clinical populations, limiting generalizability to healthy individuals. The exact form of artichoke (e.g., leaf extract, juice) was not consistently reported, and the effective dose range varied across studies.
Generated Jul 15, 2026