Skip to main content
Evidence-Based Supplement Research
Evidence-Based Supplement Research
Pillser
Search
Sign UpLog In

Black Cumin and Reduced Aspartate Aminotransferase Level

Research synthesisLow evidenceSmall effect3 studies · 1 beneficial · 2 neutral · 0 harmful

Across 3 studies, 1 reported a beneficial small effect on reducing aspartate aminotransferase (AST), while 2 found no significant effect. The overall evidence is mixed, with a neutral predominant finding. The most studied dose range is broad (200–4600 mg/day) and the median study duration is 19 days.

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Many of the included studies did not reach statistical significance, suggesting the effect may be small or inconsistent. The beneficial finding comes from a large meta-analysis, but the other two studies found no significant effect. Median study duration was 19 days, which may be too short to observe changes in AST levels.

Generated Jul 10, 2026
Doses used in studies
  • mL/every 8 hours: 2.5 (median 2.5, IQR 2.5–2.5) — 1 study
  • mg/day: 200–4,600 (median 2,400, IQR 200–4,600) — 1 study
Time to effect
Median: 2.6 weeks · IQR 13 days–3.5 weeks · Range 7 days–4.3 weeks — Reported in 2 of 3 studies
Safety in these studies
3 of 3 papers
Back to top