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Evidence-Based Supplement Research
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Black Cumin and Reduced Creatinine Level

Research synthesisLow evidenceSmall effect3 studies · 1 beneficial · 2 neutral · 0 harmful

Across 3 studies, only 1 reported a small beneficial effect of black cumin on reducing creatinine levels, while 2 found no significant effect. Effect sizes were consistently small across all studies. Doses varied widely (200–4600 mg/day in the beneficial study), and the median study duration was 19 days.

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Only 1 of 3 studies reached statistical significance; the effect may be smaller than that single study suggests. Study durations were short (median 19 days), which may not capture longer-term effects on creatinine.

Generated Jul 10, 2026
Doses used in studies
  • mL/every 8 hours: 2.5 (median 2.5, IQR 2.5–2.5) — 1 study
  • mg/day: 200–4,600 (median 2,400, IQR 200–4,600) — 1 study
Time to effect
Median: 2.6 weeks · IQR 13 days–3.5 weeks · Range 7 days–4.3 weeks — Reported in 2 of 3 studies
Safety in these studies
3 of 3 papers
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