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Evidence-Based Supplement Research
Evidence-Based Supplement Research
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Black Cumin and Reduced Systolic Blood Pressure

Research synthesisModerate evidenceSmall effect4 studies · 4 beneficial · 0 neutral · 0 harmful

Across 4 studies, all reported beneficial effects on systolic blood pressure, with a predominant small effect size (3 small, 1 moderate). The most comprehensive meta-analyses showed a reduction of approximately 3 mmHg (e.g., -3.25 mmHg, 95% CI: -4.44 to -2.06). Effects were observed in diverse populations including patients with metabolic diseases and postmenopausal women, with study durations typically ranging from 4 to 8 weeks.

Caveats: Available evidence is overwhelmingly positive, but the evidence base is small (only 4 studies) — conclusions should be considered preliminary, and clinical literature in this area is subject to publication bias. Additionally, effects are modest and based on a limited number of trials, so clinical significance may vary.

Generated Jul 4, 2026
Doses used in studies
  • mg/day: 200–4,600 (median 1,500, IQR 250–3,650) — 2 studies
Time to effect
Median: 4.5 weeks · IQR 2.8 weeks–6.3 weeks · Range 7 days–8 weeks — Reported in 2 of 4 studies
4 of 4 papers
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