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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Black Cumin and Reduced Triglyceride Levels

Research synthesisModerate evidenceModerate effect3 studies · 2 beneficial · 1 neutral · 0 harmful

Across 3 meta-analyses, 2 reported beneficial effects on triglyceride levels, with effect sizes ranging from moderate to large, while 1 study found no significant effect. The most robust evidence comes from a 2025 dose-response meta-analysis (n=5,026), which showed a moderate beneficial effect with doses from 200 to 4600 mg/day over 7 days. Effects predominantly favor supplementation, though the evidence base is small and study durations were short.

  • Effective dose range: 200 to 4600 mg/day

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Two of the three studies were statistically significant and beneficial, but one meta-analysis restricted to T2DM patients found no significant effect, suggesting the benefit may not extend uniformly to clinical populations. All included studies are meta-analyses, which aggregate data from multiple RCTs, but the single study reporting duration had only 7 days of supplementation — longer-term effects remain unclear.

Generated Jun 4, 2026
Doses used in studies
  • mg/day: 200–4,600 (median 2,400, IQR 2004,600) 1 study
Time to effect
Median: 7 days · IQR 7 days7 days · Range 7 days7 days — Reported in 1 of 3 studies
3 of 3 papers
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