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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Hops and Improved Gut Microbiota Composition

Doses used in studies

mg/day: 24 (median 24, IQR 24–24) — 1 study

Time to effect

Median: 8 weeks · IQR 8 weeks–8 weeks · Range 8 weeks–8 weeks — Reported in 1 of 1 study

Safety in these studies

Overall tolerabilityReported
We conducted a randomized, triple-blinded, placebo-controlled clinical trial (ClinicalTrials.gov NCT03735420) to determine safety and tolerability of XN in healthy adults.
from: Gut enterotype-dependent modulation of gut microbiota and their metabolism in response to

1 of 1 paper

Gut enterotype-dependent modulation of gut microbiota and their metabolism in response to xanthohumol supplementation in healthy adults.
- 2024-02-15
- RCT
- Gut microbes 16(1)
- - Paige E Jamieson
  - Eli B Smart
  - John A Bouranis
  - Jaewoo Choi
  - Robert E Danczak
  - Carmen P Wong
  - Ines L Paraiso
  - Claudia S Maier
  - Emily Ho
  - Thomas J Sharpton
  - Thomas O Metz
  - Ryan Bradley
  - Jan F Stevens
- PubMed: 38358253
- DOI: 10.1080/19490976.2024.2315633
2 Insights on
- Improved Gut Microbiota Composition
- High evidence
- Adults
Although XN did not significantly change gut microbiota composition, it did re-shape individual taxa in an enterotype-dependent manner.
Effect
Neutral
Effect size
Small
Significant
No
Dose
24 mg/day