Clinical effectiveness and safety of total glucosides of paeony as an immunomodulator in patients with refractory oral lichen planus: A multicenter, pragmatic, randomized controlled trial.
- 2026-02
- RCT · n = 448
- Phytomedicine : international journal of phytotherapy and phytopharmacology 151
- Yiwen Deng
- Leilei Zhou
- Na Li
- Fan Huang
- Guanhuan Du
- Yufeng Wang
- Jian Meng
- Shijie Chen
- Xiufeng Wei
- Wenmei Wang
- Guoyao Tang
- PubMed: 41539096
- DOI: 10.1016/j.phymed.2026.157770
- High evidence
- Large Human Trial
- Clinical
Patients receiving TGP also experienced greater improvements in sleep quality (PSQI responder rate: HR 1.49, p = 0.038)
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes
- Dose
- 0.6 g three times daily