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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Perilla and Reduced Blood Cholesterol

Time to effect

Median: 3.5 months · IQR 9.4 weeks–4.7 months · Range 4 weeks–6 months — Reported in 2 of 2 studies

Safety in these studies

Overall tolerabilityReported
Perilla seed oil had no adverse effect to kidney, liver, blood components or glucose metabolism.
from: Outcomes of Perilla Seed Oil as an Additional Neuroprotective Therapy in Patients with Mil

2 of 2 papers

Outcomes of Perilla Seed Oil as an Additional Neuroprotective Therapy in Patients with Mild to Moderate Dementia: A Randomized Control Trial.
- 2019-02-04
- RCT · n = 182
- Current Alzheimer research 16(2)
- - Chuntida Kamalashiran
  - Kusuma Sriyakul
  - Junya Pattaraarchachai
  - Sombat Muengtaweepongsa
- PubMed: 30543172
- DOI: 10.2174/1567205016666181212153720
3 Insights on
- Reduced Blood Cholesterol
- High evidence
- Large Human Trial
- Clinical
the total cholesterol and LDL cholesterol were significantly lower in the experimental group.
Effect
Beneficial
Effect size
Small
Significant
Yes
Effects of perilla seed oil supplementation on leukotriene generation by leucocytes in patients with asthma associated with lipometabolism.
- 2000
- Clinical Trial
- International archives of allergy and immunology 122(2)
- - M Okamoto
  - F Mitsunobu
  - K Ashida
  - T Mifune
  - Y Hosaki
  - H Tsugeno
  - S Harada
  - Y Tanizaki
  - M Kataoka
  - K Niiya
  - M Harada
- PubMed: 10878492
- DOI: 10.1159/000024369
7 Insights on
- Reduced Blood Cholesterol
- Moderate evidence
- Clinical
Serum levels of total cholesterol ... were significantly decreased by dietary supplementation in group A after 4 weeks
Effect
Beneficial
Effect size
Small
Significant
Yes
Dose
dietary supplementation (amount not specified)