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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Red Ginseng and Reduced Fatigue

Doses used in studies

mg/day: 2,000 (median 2,000, IQR 2,000–2,000) — 1 study

Time to effect

Median: 3.7 months · IQR 3.7 months–3.7 months · Range 3.7 months–3.7 months — Reported in 1 of 2 studies

Safety in these studies

neutropeniaIncreased risk
Although neutropenia was more frequent in KRG than placebo, the incidence of all adverse events was similar.
from: Korean red ginseng for cancer-related fatigue in colorectal cancer patients with chemother
Overall tolerabilityNo significant difference
the incidence of all adverse events was similar.
from: Korean red ginseng for cancer-related fatigue in colorectal cancer patients with chemother

2 of 2 papersPopulation:

The Effects of Korean Red Ginseng on Biological Aging and Antioxidant Capacity in Postmenopausal Women: A Double-Blind Randomized Controlled Study.
- 2021-09-02
- RCT · n = 63
- Nutrients 13(9)
- - Tae-Ha Chung
  - Ji-Hye Kim
  - So-Young Seol
  - Yon-Ji Kim
  - Yong-Jae Lee
- PubMed: 34578969
- DOI: 10.3390/nu13093090
1 Insight on
- Reduced Fatigue
- High evidence
- Rigorous Journal
- Adults
the fatigue severity scale (KRG group: -7 ± 12, placebo group: -1 ± 11, p = 0.033) decreased significantly more in the KRG group than the placebo group.
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Korean red ginseng for cancer-related fatigue in colorectal cancer patients with chemotherapy: A randomised phase III trial.
- 2020-05
- RCT · n = 219
- European journal of cancer (Oxford, England : 1990) 130
- - Jin Won Kim
  - Sae Won Han
  - Jae Yong Cho
  - Ik-Joo Chung
  - Jong Gwang Kim
  - Kyung Hee Lee
  - Keon Uk Park
  - Sun Kyung Baek
  - Sang Cheul Oh
  - Myung Ah Lee
  - Doyeun Oh
  - Byoungyong Shim
  - Joong Bae Ahn
  - Dongbok Shin
  - Jae Won Lee
  - Yeul Hong Kim
- PubMed: 32172198
- DOI: 10.1016/j.ejca.2020.02.018
6 Insights on
- Reduced Fatigue
- High evidence
- Large Human Trial
- Clinical
there were improvements in 'Fatigue right now' ... at 16 weeks (P = 0.045)
Effect
Beneficial
Effect size
Small
Significant
Yes
Dose
2000 mg/day