Red Grape and Increased HDL Cholesterol Levels

Doses used in studies

mg/day: 300 (median 300, IQR 300–300) — 1 study

Time to effect

Median: 2.8 months · IQR 2.8 months–2.8 months · Range 2.8 months–2.8 months — Reported in 1 of 1 study

1 of 1 paper

Grape seed extract supplementation along with a restricted-calorie diet improves cardiovascular risk factors in obese or overweight adult individuals: A randomized, placebo-controlled trial.

2020-10-12
RCT
Phytotherapy research : PTR 35(2)
- Reyhaneh Yousefi
- Maryam Parandoosh
- Hoda Khorsandi
- Nima Hosseinzadeh
- Masoumeh Madani Tonekaboni
- Atoosa Saidpour
- Hossein Babaei
- Arman Ghorbani

PubMed: 33044768
DOI: 10.1002/ptr.6859

6 Insights on

Increased HDL Cholesterol Levels

High evidence
Clinical

Levels of high-density lipoprotein cholesterol (HDL-C) and HDL-C/low-density lipoprotein cholesterol (LDL-C) significantly increased in the GSE group as compared with the placebo group at week 12 (p = .03 and .008, respectively, adjusted for age, sex, energy and saturated fatty acid intake).

Effect: Beneficial
Effect size: Moderate
Significant: Yes
Dose: 300 mg/day