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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Red Grape and Reduced Triglyceride Levels

Doses used in studies

mg/day: 520 (median 520, IQR 520–520) — 1 study

Time to effect

Median: 8.6 weeks · IQR 8.6 weeks–8.6 weeks · Range 8.6 weeks–8.6 weeks — Reported in 1 of 2 studies

2 of 2 papers

Efficacy of flavonoids in non-alcoholic fatty liver disease: an updated systematic review and meta-analysis.
- 2025-09-15
- Systematic Review · n = 689
- Frontiers in nutrition 12
- - Qianqian Liu
  - Haodi Luan
  - Zhijiao Duan
  - Jing Ai
  - Yan Wang
  - Ping Chen
- PubMed: 41031363
- DOI: 10.3389/fnut.2025.1660065
10 Insights on
- Reduced Triglyceride Levels
- High evidence
- Clinical
Flavonoids intervention significantly decreased ... triglycerides (TG)
Effect
Beneficial
Effect size
Moderate
Significant
Yes
The effects of grape seed extract supplementation on cardiovascular risk factors, liver enzymes and hepatic steatosis in patients with non-alcoholic fatty liver disease: a randomised, double-blind, placebo-controlled study.
- 2024-05-16
- RCT · n = 25
- BMC complementary medicine and therapies 24(1)
- - Parisa Ghanbari
  - Davoud Raiesi
  - Roghayeh Alboebadi
  - Ahmad Zarejavid
  - Mostafa Dianati
  - Hamidreza Razmi
  - Hadi Bazyar
- PubMed: 38755622
- DOI: 10.1186/s12906-024-04477-3
18 Insights on
- Reduced Triglyceride Levels
- High evidence
- Clinical
insulin, HOMA-IR, TC, TG, LDL-c, ALT, AST, AST/ALT, SBP, DBP and MAP decreased and QUICKi and HDL-c increased significantly (p-value for all < 0.05)
Effect
Beneficial
Effect size
Small
Significant
Yes
Dose
520 mg/day