Resveratrol and Reduced Waist Circumference

Research synthesisModerate evidenceSmall effect3 studies · 3 beneficial · 0 neutral · 0 harmful

Across 3 meta-analyses, all reported beneficial small-sized effects of resveratrol supplementation on reducing waist circumference, with reductions ranging from -0.80 cm to -1.93 cm. The evidence primarily comes from populations with overweight/obesity or type 2 diabetes. No consistent dose range or form was reported across studies.

Studied populations: individuals with overweight/obesity and type 2 diabetes

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Additionally, doses and forms were not consistently reported, limiting the ability to make specific recommendations.

Generated Jul 18, 2026

3 of 3 papers

The effect of resveratrol supplementation on anthropometric indices, adiponectin and leptin levels in individuals with overweight and obesity: a graded, systematic review and meta-analysis of randomized controlled trials.
- 2025-12-27
- Meta-Analysis · n = 1,005
- International journal of obesity (2005) 50(3)
- - Azin Setayesh
  - Pishva Arzhang
  - Mohammadreza Moradi Baniasadi
  - Maryam Lahouti
  - Leila Azadbakht
- PubMed: 41455817
- DOI: 10.1038/s41366-025-01994-0
9 Insights on
- Reduced Waist Circumference
- High evidence
- Clinical
However, resveratrol supplementation significantly reduced waist circumference (WC) (WMD: -1.93 cm; 95% CI: -3.10, -0.76; P = 0.001)
Effect
Beneficial
Effect size
Small
Significant
Yes
A Systematic Review and Meta-Analysis of Randomized Controlled Trials on the Impact of Resveratrol Supplementation on Anthropometric Indices in Patients With Type 2 Diabetes.
- 2025-08-21
- Meta-Analysis · n = 614
- Phytotherapy research : PTR 39(10)
- - Maryam Lahouti
  - Pishva Arzhang
  - Leila Azadbakht
- PubMed: 40842160
- DOI: 10.1002/ptr.70074
5 Insights on
- Reduced Waist Circumference
- High evidence
- Clinical
WC (WMD: -0.80 cm, 95% CI: -1.35 to -0.24, p = 0.005)
Effect
Beneficial
Effect size
Small
Significant
Yes
Effects of resveratrol supplementation on multiple health outcomes: an umbrella review of systematic reviews and meta-analyses of randomized controlled trials.
- 2026-04-15
- Meta-Analysis
- Nutrition journal 25(1)
- - Jia-Nan Sun
  - Rui Yang
  - Li Fang
  - Yun-Jia Li
  - Wei-Yi Xing
  - Ming-Li Sun
  - Lang Wu
  - Qi-Jun Wu
  - Ting-Ting Gong
- PubMed: 41987155
- DOI: 10.1186/s12937-026-01319-5
11 Insights on
- Reduced Waist Circumference
- High evidence
- Clinical
reducing waist circumference (mean difference [MD] = -0.80 cm, 95% CI = -1.40, -0.20)
Effect
Beneficial
Effect size
Small
Significant
Yes

Resveratrol and Reduced Waist Circumference

The effect of resveratrol supplementation on anthropometric indices, adiponectin and leptin levels in individuals with overweight and obesity: a graded, systematic review and meta-analysis of randomized controlled trials.

A Systematic Review and Meta-Analysis of Randomized Controlled Trials on the Impact of Resveratrol Supplementation on Anthropometric Indices in Patients With Type 2 Diabetes.

Effects of resveratrol supplementation on multiple health outcomes: an umbrella review of systematic reviews and meta-analyses of randomized controlled trials.