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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Thistle and Improved Liver Function

Safety in these studies

Overall tolerabilityReported
proven it's safety
from: Recapitulation of Evidence of Phytochemical, Pharmacokinetic and Biomedical Application of
Overall tolerabilityReported
Overall, supplementation was not associated with serious adverse events in the included trials.
from: Impact of Dietary Supplements on Clinical Outcomes and Quality of Life in Patients with Br
bloatingReported
proven it's safety and offers mild effect like nausea, diarrhea and bloating
from: Recapitulation of Evidence of Phytochemical, Pharmacokinetic and Biomedical Application of
diarrheaReported
proven it's safety and offers mild effect like nausea, diarrhea and bloating
from: Recapitulation of Evidence of Phytochemical, Pharmacokinetic and Biomedical Application of
nauseaReported
proven it's safety and offers mild effect like nausea, diarrhea and bloating
from: Recapitulation of Evidence of Phytochemical, Pharmacokinetic and Biomedical Application of

2 of 2 papersPopulation:

Impact of Dietary Supplements on Clinical Outcomes and Quality of Life in Patients with Breast Cancer: A Systematic Review.
- 2025-03-11
- Systematic Review · n = 45
- Nutrients 17(6)
- - Luca Scafuri
  - Carlo Buonerba
  - Oriana Strianese
  - Evandro de Azambuja
  - Michela Palleschi
  - Vittorio Riccio
  - Vincenzo Marotta
  - Concetta Scocca
  - Giovanni Riccio
  - Carla Errico
  - Grazia Arpino
  - Giuseppe Di Lorenzo
- PubMed: 40290044
- DOI: 10.3390/nu17060981
7 Insights on
- Improved Liver Function
- High evidence
- Rigorous Journal
- Clinical
Silymarin showed potential for hepatoprotective effects.
Effect
Beneficial
Effect size
Small
Significant
Yes
Recapitulation of Evidence of Phytochemical, Pharmacokinetic and Biomedical Application of Silybin.
- 2021-07-27
- Review
- Drug research 71(09)
- - Anas Islam
  - Anuradha Mishra
  - Md Aftab Siddiqui
  - Saman Siddiquie
- PubMed: 34318464
- DOI: 10.1055/a-1528-2721
11 Insights on
- Improved Liver Function
- Low evidence
It has been used traditionally for the treatment of various liver disorders like cirrhosis, jaundice, and hepatitis.
Effect
Beneficial
Effect size
Moderate
Significant
Yes