Thistle and Reduced Total Cholesterol Levels

• Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications.

  • 2025-08-01
  • Meta-Analysis · n = 2,283
  • Asia Pacific journal of clinical nutrition 34(4)
  • • Zhen Zhang
    • Shuai Li
    • Jianjun Sun

  • PubMed: 40738719
  • DOI: 10.6133/apjcn.202508_34(4).0003

  6 Insights on

  • Reduced Total Cholesterol Levels

  • High evidence
  • Clinical

  Total cholesterol levels were reduced by silymarin+Mediterranean hypocaloric diets (SMD: -0.39 (-0.81, 0.03), p=0.072)

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

• Silibinin as a major component of milk thistle seed provides promising influences against diabetes and its complications: a systematic review.

  • 2024-05-27
  • Systematic Review
  • Naunyn-Schmiedeberg's archives of pharmacology 397(10)
  • • Parisa Zare Mehrjerdi
    • Sara Asadi
    • Elham Ehsani
    • Vahid Reza Askari
    • Vafa Baradaran Rahimi

  • PubMed: 38801454
  • DOI: 10.1007/s00210-024-03172-x

  15 Insights on

  • Reduced Total Cholesterol Levels

  • High evidence

  ameliorated levels of triglyceride (TG), cholesterol, low-density lipoprotein (LDL), and high-density lipoprotein (HDL)

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes