Turmeric and Reduced Low-Density Lipoprotein Level

Across 3 studies, 2 reported beneficial effects on reducing low-density lipoprotein (LDL) cholesterol, with effect sizes ranging from small to moderate, while 1 study found no significant difference. The most consistent evidence comes from a meta-analysis of 63 RCTs in people with type 2 diabetes or hyperglycemia showing a small but significant reduction (mean difference -5.95 mg/dL). The median study duration was 90 days (from one study), and the evidence primarily covers clinical populations with metabolic conditions. Overall, the evidence suggests a beneficial effect, but the magnitude varies and the data are limited.

• Studied populations: people with type 2 diabetes, hyperglycemia, metabolic syndrome, or hemodialysis

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. One small RCT in hemodialysis patients found no significant effect, suggesting benefit may not extend to all clinical populations. No form data were available; the form of turmeric (e.g., standardized curcumin extract) may influence outcomes but could not be assessed. The meta-analysis provides the strongest support, but includes only people with hyperglycemia, limiting generalizability.