Bifidobacterium animalis subsp. lactis BB-12 and Reduced Body Weight

• Bifidobacterium animalis subsp. lactis BB-12 attenuates diabetic retinopathy through gut microbiota modulation: evidence for the gut-retinal axis.

  • 2025-11-06
  • Frontiers in cellular and infection microbiology 15
  • • Jiayi Lin
    • Yaqi Cheng
    • Yumin Ling
    • Simin Gu
    • Haocheng Zhu
    • Meng Li
    • Huan Yu
    • Jianbing Li
    • Qian Luo
    • Weihua Li
    • Shiqi Ling

  • PubMed: 41278472
  • DOI: 10.3389/fcimb.2025.1681943

  9 Insights on

  • Reduced Body Weight

  • Low evidence
  • Animal Study

  BB-12 reduced obesity, decreased hepatic steatosis, improved retinal blood vessel health and vision

  Effect

  Beneficial

  Effect size

  Moderate

• Bifidobacterium animalis subsp. lactis BB-12 Has Effect Against Obesity by Regulating Gut Microbiota in Two Phases in Human Microbiota-Associated Rats

  • 2022-01-10
  • Clinical Trial
  • Frontiers in Nutrition 8
  • • Kemin Mao
    • Jie Gao
    • Xianghong Wang
    • Xiyu Li
    • S. Geng
    • Tuo Zhang
    • F. A. Sadiq
    • Yaxin Sang

  • PubMed: 35083265
  • DOI: 10.3389/fnut.2021.811619

  13 Insights on

  • Reduced Body Weight

  • Low evidence
  • Animal Study

  A decrease in body weight and the *Firmicutes/Bacteroidetes* ratio were also observed at week 3.

  Effect

  Beneficial

  Effect size

  Moderate