Bifidobacterium animalis subsp. lactis Bi-07 and Improved Lactose Digestion

• Bifidobacterium animalis subsp. lactis Bi-07 supports lactose digestion in vitro and in randomized, placebo- and lactase-controlled clinical trials

  • 2022-12
  • RCT
  • The American Journal of Clinical Nutrition 116(6)
  • • Pia Rasinkangas
    • S. Forssten
    • M. Marttinen
    • A. Ibarra
    • G. Bothe
    • J. Junnila
    • R. Uebelhack
    • Y. Donazzolo
    • A. Ouwehand

  • PubMed: 36149331
  • DOI: 10.1093/ajcn/nqac264

  3 Insights on

  • Improved Lactose Digestion

  • High evidence

  Bi-07 was superior to placebo in reducing BHC [iAUC, parts per million (ppm) ∙ h] in both trials... Bi-07 has high lactase activity, and in 2 clinical trials, it supported lactose digestion in individuals with lactose intolerance.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

• Lactose intolerance and probiotics: from pathophysiological mechanisms to clinical applications.

  • 2026-03-17
  • Review
  • Antonie van Leeuwenhoek 119(4)
  • • Tsachi Tsadok Perets
    • Rachel Gingold-Belfer
    • Ram Dickman

  • PubMed: 41843249
  • DOI: 10.1007/s10482-026-02278-x

  3 Insights on

  • Improved Lactose Digestion

  • Low evidence

  This review aims to explore the evidence supporting the use of probiotics as a potential treatment strategy to alleviate the symptoms of lactose intolerance by modulating colonic metabolism and enhancing lactose digestion.

  Effect

  Beneficial

  Effect size

  Small