Bifidobacterium breve VPro 52 and Improved Insulin Sensitivity

• Supplementation with Bifidobacterium breve BR03 and B632 strains improved insulin sensitivity in children and adolescents with obesity in a cross-over, randomized double-blind placebo-controlled trial.

  • 2021-07
  • RCT · n = 101
  • Clinical Nutrition 40(7)
  • • Arianna Solito
    • Nicole Bozzi Cionci
    • M. Calgaro
    • M. Caputo
    • L. Vannini
    • Iderina Hasballa
    • Francesca Archero
    • E. Giglione
    • R. Ricotti
    • G. Walker
    • A. Petri
    • Emanuela Agosti
    • G. Bellomo
    • G. Aimaretti
    • G. Bona
    • S. Bellone
    • A. Amoruso
    • M. Pane
    • D. Di Gioia
    • N. Vitulo
    • F. Prodam

  • PubMed: 34229263
  • DOI: 10.1016/j.clnu.2021.06.002

  6 Insights on

  • Improved Insulin Sensitivity

  • High evidence

  Probiotics improved insulin sensitivity at fasting (QUICKI, 0.013 CI95%0.0-0.03) and during OGTT (ISI, 0.654 CI95%-0.11-1.41).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  No

• Antiobesity Effects of Bifidobacterium breve Strain B-3 Supplementation in a Mouse Model with High-Fat Diet-Induced Obesity

  • 2010-08-23
  • Clinical Trial
  • Bioscience, Biotechnology, and Biochemistry 74(8)
  • • S. Kondo
    • J. Xiao
    • T. Satoh
    • T. Odamaki
    • Sachiko Takahashi
    • H. Sugahara
    • T. Yaeshima
    • K. Iwatsuki
    • A. Kamei
    • K. Abe

  • PubMed: 20699581
  • DOI: 10.1271/bbb.100267

  9 Insights on

  • Improved Insulin Sensitivity

  • Low evidence
  • Highly Cited
  • Animal Study

  B. breve B-3 supplementation... improved the serum levels of... insulin.

  Effect

  Beneficial

  Effect size

  Large