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Evidence-Based Supplement Research
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Bifidobacterium lactis Bb-02 and Reduced Inflammation

Research synthesisLow evidenceMixed effect size3 studies · 3 beneficial · 0 neutral · 0 harmful

Across 3 studies, all reported beneficial effects of Bifidobacterium lactis Bb-02 on reducing inflammation, with effect sizes ranging from small to moderate. The most robust evidence comes from a meta-analysis in subjects with type 2 diabetes (n=3390) showing small beneficial effects on inflammatory markers. Evidence base is small (only 3 studies) — conclusions should be considered preliminary.

  • Studied populations: subjects with type 2 diabetes, women with gestational diabetes, patients with neurodegenerative diseases

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. None of the studies reported statistical significance, and doses and forms were not consistently described. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed).

Generated May 12, 2026
3 of 3 papers
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