Bifidobacterium lactis MAK16B42L and Improved Immune Function

• Consumption of Dairy Yogurt Containing Lactobacillus paracasei ssp. paracasei, Bifidobacterium animalis ssp. lactis and Heat-Treated Lactobacillus plantarum Improves Immune Function Including Natural Killer Cell Activity

  • 2017-05-31
  • RCT · n = 200
  • Nutrients 9(6)
  • • Ayoung Lee
    • Young Ju Lee
    • H. J. Yoo
    • Minkyung Kim
    • Yeeun Chang
    • Dong Seog Lee
    • J. H. Lee

  • PubMed: 28561762
  • DOI: 10.3390/nu9060558

  14 Insights on

  • Improved Immune Function

  • High evidence
  • Highly Cited

  Natural killer (NK) cell activity, interleukin (IL)-12 and immunoglobulin (Ig) G1 levels were significantly increased in the test group at twelve weeks compared to baseline. Additionally, the test group had significantly greater increases in serum NK cell activity and interferon (IFN)-γ and IgG1 than placebo group.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

• Enhancing immunity by dietary consumption of a probiotic lactic acid bacterium (Bifidobacterium lactis HN019): optimization and definition of cellular immune responses

  • 2000-11-01
  • RCT · n = 50
  • European Journal of Clinical Nutrition 54(11)
  • • B. Chiang
    • Y. Sheih
    • LH Wang
    • Chuh-K. Liao
    • H. Gill

  • PubMed: 11114680
  • DOI: 10.1038/sj.ejcn.1601093

  16 Insights on

  • Improved Immune Function

  • High evidence
  • Highly Cited

  While consumption of LFM alone had no significant effect on immune responses, stage 2 results indicated significantly enhanced PMN cell phagocytosis and NK cell tumour killing activity following consumption of milk containing B. lactis.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes