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Evidence-Based Supplement Research
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Bifidobacterium plantarum and Improved Gut Microbiota Balance

Research synthesisLow evidenceModerate effect6 studies · 6 beneficial · 0 neutral · 0 harmful

Across 6 studies (all reviews), 6 out of 6 report beneficial effects of Bifidobacterium plantarum on gut microbiota balance, with effect sizes predominantly moderate. No doses, forms, or study durations were reported in the available evidence. The evidence comes entirely from narrative or scoping reviews, most published in 2025–2026, covering diverse populations including CKD patients, individuals with obesity, and livestock.

  • Studied populations: patients with chronic kidney disease (CKD stages 3–5), individuals with obesity, livestock and poultry

Caveats: Available evidence is overwhelmingly positive (6 of 6 studies beneficial), but all studies are reviews — no original controlled trials were among the 6 papers. Clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). None of the studies reported statistically significant findings or provided extractable dose, form, or duration data, limiting actionable conclusions. Evidence base is small (only 6 studies) and entirely review-level, so conclusions should be considered preliminary.

Generated Jun 11, 2026
7 of 7 papers
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