Bifidobacterium plantarum and Improved Intestinal Barrier Function

• Lactiplantibacillus plantarum Q180 supplementation restores high-fat diet-induced gut dysbiosis and intestinal barrier dysfunction in mice.

  • 2026-01-23
  • Journal of applied microbiology 137(2)
  • • Minseo Cho
    • Jaeryang Chu
    • Chae-Won No
    • Yeon-Woo Kim
    • Jiwoo Lee
    • Hyunchae Joung
    • Yoo Jin Kwon
    • Chang Hun Shin
    • Jisu Lee
    • Jung-Heun Ha

  • PubMed: 41574946
  • DOI: 10.1093/jambio/lxag021

  4 Insights on

  • Improved Intestinal Barrier Function

  • Low evidence
  • Animal Study

  LPQ supplementation restored microbial balance... These microbial alterations were accompanied by decreased endotoxin levels, upregulation of epithelial tight junction genes (Zo-1, Ocln, and Claudin1), and downregulation of mucin genes (Muc2 and Muc4).

  Effect

  Beneficial

  Effect size

  Moderate

• Therapeutic Mechanisms of Lactiplantibacillus plantarum NXU0014 Against Chronic Alcohol-Induced Liver Injury Mediated by Gut-Liver Axis Modulation.

  • 2026-01
  • Molecular nutrition & food research 70(1)
  • • Quan Ji
    • Yanhong Wang
    • Longxuan Huo
    • Chen Qiao
    • Fuqi Li
    • Fan Yang
    • Lin Pan

  • PubMed: 41543328
  • DOI: 10.1002/mnfr.70375

  4 Insights on

  • Improved Intestinal Barrier Function

  • Low evidence
  • Rigorous Journal
  • Animal Study

  Intervention with NXU0014 ... repaired the intestinal barrier.

  Effect

  Beneficial

  Effect size

  Moderate