Bifidobacterium plantarum and Improved Irritable Bowel Syndrome Symptoms

• Efficacy of Specific Probiotic Strains in Subtypes of Irritable Bowel Syndrome: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

  • 2025-12-31
  • Meta-Analysis
  • Medicina (Kaunas, Lithuania) 62(1)
  • • Abdulrahman Saud Almalki
    • Norah Yhya Jaafari
    • Norah Ghalib Aldossari
    • Anwar Ayed Alharbi
    • Abdulrahman Abdullah Alrdeeni
    • Alanoud Abdullah Alshareef
    • Abdulrahman Abed Al-Subhi
    • Ammar Faisal Alsubhi
    • Muath Salem Alsubhi
    • Abdullah Almaqhawi

  • PubMed: 41597375
  • DOI: 10.3390/medicina62010089

  4 Insights on

  • Improved Irritable Bowel Syndrome Symptoms

  • High evidence

  Probiotics significantly reduced intestinal discomfort overall (MD: -93.9; 95% CI -133.1 to -54.7; p < 0.00001) and the IBS-Severity Scoring System. Probiotics showed a clinically significant overall improvement (OR 1.71; 95% CI 1.26-2.33; p = 0.0006) when compared to a placebo.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

• Global landscape analysis of clinical trials on gut microbiota modulation therapies for irritable bowel syndrome.

  • 2026-03-02
  • Review
  • Frontiers in medicine 13
  • • Yiting Luo
    • Junjie Cao
    • Bingbing Li
    • Junwen Wang
    • Tianxiang Geng
    • Zining Luo
    • Jiebin Xie

  • PubMed: 41852522
  • DOI: 10.3389/fmed.2026.1737537

  1 Insight on

  • Improved Irritable Bowel Syndrome Symptoms

  • Low evidence

  Systematically analyze the global landscape of interventional clinical trials on gut microbiota modulation (GMM) therapies for irritable bowel syndrome (IBS)... Probiotics led (single-strain: Lactobacillus/Bifidobacterium; multi-strain: Lactobacillus + Bifidobacterium)...

  Effect

  Beneficial

  Effect size

  Moderate