Best Supplements for Improved Irritable Bowel Syndrome Symptoms
Ranked by research evidence. Compare 32 supplements across 38 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Moderate evidence4 studies
Across 4 studies, 3 reported beneficial effects of Lactobacillus plantarum 299v on irritable bowel syndrome symptoms, with effect sizes ranging from moderate to large. The predominant effect size is large, and one randomized controlled trial found 95% of patients improved vs 15% on placebo. The median study duration was 28 days, but effects have been reported with longer treatment (e.g., 12 weeks), and doses varied, with one study using 1×10^10 CFU/day.
Dose: 1×10^10 CFU/day
32 supplements
- ModerateLactobacillus plantarum 299vAcross 4 studies, 3 reported beneficial effects of Lactobacillus plantarum 299v on irritable bowel syndrome symptoms, with effect sizes ranging from moderate to large. The predominant effect size is large, and one randomized controlled trial found 95% of patients improved vs 15% on placebo. The median study duration was 28 days, but effects have been reported with longer treatment (e.g., 12 weeks), and doses varied, with one study using 1×10^10 CFU/day. · Dose: 1×10^10 CFU/day3 beneficial1 neutral4 studies