Across 3 studies (all reviews or animal model research), all reported beneficial effects of Bifidobacterium plantarum on reducing oxidative stress, with effect sizes ranging from small to moderate. The evidence base is very limited, with no statistically significant findings and no human trial data available. No consistent dose, form, or population can be identified from these studies.
Caveats: All 3 studies are low-quality — two are narrative reviews and one is an animal study (rats). No human clinical trials are included. The beneficial effects reported are from indirect mentions within broader reviews, not from studies specifically designed to test Bifidobacterium plantarum for oxidative stress reduction. No statistical significance was reported in any study. The evidence is insufficient to draw conclusions for human supplementation.
Phytoantioxidants such as polyphenols directly neutralize I/R-induced reactive oxygen species (ROS), which promote microvascular recovery and neuronal survival.
Lacocaseibacillus casei, Lactiplantibacillus plantarum, and Bifidobacterium bifidum mitigate CRC by lowering oxidative stress and lipid peroxidation
synbiotic supplementation enhanced antioxidant levels (SOD and GSH), decreased oxidants (MDA)