Lactiplantibacillus plantarum KABP-023 and Improved Gut Microbiota Diversity

• A Randomized, Double-Blind, Placebo-Controlled Trial to Assess the Efficacy and Safety of Lactiplantibacillus plantarum CJLP243 in Patients with Functional Diarrhea and High Fecal Calprotectin Levels

  • 2022-01-17
  • RCT · n = 24
  • Nutrients 14(2)
  • • Minah H. Jung
    • Susie Jung
    • Nam-Kyu Kim
    • H. Ahn
    • H. Yun
    • Kyu-Nam Kim

  • PubMed: 35057571
  • DOI: 10.3390/nu14020389

  4 Insights on

  • Improved Gut Microbiota Diversity

  • High evidence

  The levels of Leuconostoc genus organisms in the gut microbiota composition in the probiotic group increased significantly after the end of the study compared with the baseline values.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

• Lactiplantibacillus plantarum WJL administration during pregnancy and lactation improves lipid profile, insulin sensitivity and gut microbiota diversity in dyslipidemic dams and protects male offspring against cardiovascular dysfunction in later life.

  • 2021-05-14
  • RCT · n = 15
  • Food & Function 11(10)
  • • K. Guimarães
    • V. Braga
    • S. Noronha
    • Whyara K A Costa
    • Kassem Makki
    • J. Cruz
    • Larissa Ramalho Brandão
    • Deoclecio Alves Chianca Junior
    • E. Meugnier
    • F. Leulier
    • H. Vidal
    • M. Magnani
    • J. L. de Brito Alves

  • PubMed: 33000822
  • DOI: 10.1039/d0fo01718c

  8 Insights on

  • Improved Gut Microbiota Diversity

  • Low evidence
  • Animal Study
  • Clinical

  Administration of L. plantarum WJL to dams having maternal dyslipidemia improved gut microbiota composition, lipid profile and insulin resistance in them.

  Effect

  Beneficial

  Effect size

  Moderate