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Evidence-Based Supplement Research
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Lactobacillus acidophilus L-92 and Reduced Severity of Allergic Rhinitis Symptoms

Research synthesisLow evidenceModerate effect10 studies · 10 beneficial · 0 neutral · 0 harmful

Across 10 studies, all reported beneficial effects of Lactobacillus acidophilus L-92 on reducing severity of allergic rhinitis symptoms, with a predominant moderate effect size (8 of 10 studies). However, only 1 study reported a statistically significant finding, and all included papers are reviews (not primary clinical trials). No consistent dose, duration, or form data were available; populations studied varied widely (e.g., cancer survivors, pre-weaning calves, general adults).

Caveats: Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Additionally, many of the included studies did not reach statistical significance (only 1 of 10 reported significant findings) — the effect may be smaller than the predominant direction suggests. All database entries are reviews, not primary clinical trials, so the underlying study quality and consistency are uncertain.

Generated Jul 11, 2026
10 of 10 papers
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