Lactobacillus acidophilus L-92 and Reduced Severity of Allergic Rhinitis Symptoms

• The Efficacy and Safety of Nutritional Supplements for Cancer Supportive Care: An Umbrella Review and Hierarchical Evidence Synthesis.

  • 2026-01
  • Systematic Review
  • Integrative cancer therapies 25
  • • Sarah Benna-Doyle
    • Suzanne Grant
    • Alison Maunder
    • Jing Liu
    • Melik Ibrahim
    • Adele Cave
    • Chhiti Pandey
    • Monica Tang
    • Eng-Siew Koh
    • Geoff Delaney
    • Deep Jyoti Bhuyan
    • Victoria Choi
    • Ki Kwon
    • Maria Gonzalez
    • Susannah Graham
    • Ashanya Malalasekera
    • Carolyn Ee

  • PubMed: 41482855
  • DOI: 10.1177/15347354251405267

  11 Insights on

  • Reduced Severity of Allergic Rhinitis Symptoms

  • High evidence

  Lactobacillus acidophilus L-92 has been reported to improve allergic symptoms in some studies, but the abstract provided does not describe specific clinical outcomes for this supplement.

  Effect

  Beneficial

  Effect size

  Small

• Bacteriophages, Antibiotics and Probiotics: Exploring the Microbial Battlefield of Colorectal Cancer.

  • 2025-08-13
  • Review
  • International journal of molecular sciences 26(16)
  • • Cristian Constantin Volovat
    • Mihai Andrei Cosovanu
    • Madalina-Raluca Ostafe
    • Iolanda Georgiana Augustin
    • Constantin Volovat
    • Bogdan Georgescu
    • Simona Ruxandra Volovat

  • PubMed: 40869155
  • DOI: 10.3390/ijms26167837

  1 Insight on

  • Reduced Severity of Allergic Rhinitis Symptoms

  • Moderate evidence
  • Rigorous Journal

  consuming Lactobacillus acidophilus L-92 has been reported to improve symptoms of allergic rhinitis in randomized controlled trials

  Effect

  Beneficial

  Effect size

  Moderate

• Probiotics and human health: biological activities, nutritional aspects, immunomodulatory properties, applications, and future perspectives - a comprehensive review.

  • 2026-03-24
  • Review
  • Frontiers in immunology 16
  • • Mohamed T El-Saadony
    • Ahmed M Saad
    • Mahmoud Sitohy
    • Samar Sami Alkafaas
    • Mthokozisi Dladla
    • Soumya Ghosh
    • Dina Mostafa Mohammed
    • Essam H Ibrahim
    • Mohamed A Fahmy
    • Amr Elkelish
    • Synan F AbuQamar
    • Khaled A El-Tarabily

  • PubMed: 41953220
  • DOI: 10.3389/fimmu.2025.1713426

  10 Insights on

  • Reduced Severity of Allergic Rhinitis Symptoms

  • Low evidence

  probiotics including Lactobacillus acidophilus L-92 have been reported to improve symptoms of allergic rhinitis

  Effect

  Beneficial

  Effect size

  Moderate

• Unraveling the dynamic changes in the intestinal microbiome: impacts on pre-weaning calf health and productivity.

  • 2026-03-04
  • Review
  • Journal of animal science and biotechnology 17(1)
  • • Yang Song
    • Shubo Wen
    • Le Luo Guan

  • PubMed: 41776699
  • DOI: 10.1186/s40104-026-01354-6

  6 Insights on

  • Reduced Severity of Allergic Rhinitis Symptoms

  • Low evidence

  Lactobacillus acidophilus L-92 has been reported to help alleviate symptoms of atopic disease, including allergic rhinitis, in human studies.

  Effect

  Beneficial

  Effect size

  Moderate

• Bacterial cell envelope components of gut commensals: effects in host-microbe interaction.

  • 2026-01-30
  • Review
  • Annals of medicine 58(1)
  • • Thaís Vilela Rodrigues
    • Luís Lima de Jesus
    • Philippe Langella
    • Siomar de Castro Soares
    • Gwénaël Jan
    • Vasco Ariston de Carvalho Azevedo
    • Jean-Marc Chatel

  • PubMed: 41614625
  • DOI: 10.1080/07853890.2026.2618429

  4 Insights on

  • Reduced Severity of Allergic Rhinitis Symptoms

  • Low evidence

  Lactobacillus acidophilus L-92 has been reported to reduce symptoms of Japanese cedar pollinosis and perennial allergic rhinitis in human studies.

  Effect

  Beneficial

  Effect size

  Small

• Application of Probiotics in Foods: A Comprehensive Review of Benefits, Challenges, and Future Perspectives.

  • 2025-09-02
  • Review
  • Foods (Basel, Switzerland) 14(17)
  • • Mirjana Ž Grujović
    • Teresa Semedo-Lemsaddek
    • Katarina G Marković

  • PubMed: 40941204
  • DOI: 10.3390/foods14173088

  3 Insights on

  • Reduced Severity of Allergic Rhinitis Symptoms

  • Low evidence

  supplementation with Lactobacillus acidophilus L-92 significantly improved total nasal symptom scores, quality of life, and some immunological markers in patients with Japanese cedar pollinosis

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

• Certain fermented dairy foods as a source of multibiotics and multimetabolites: a comprehensive review.

  • 2025-11-06
  • Review
  • Frontiers in nutrition 12
  • • Duygu Ağagündüz
    • Yasemin Ertaş Öztürk
    • Büşra Ayhan
    • Tuğçe Bulmuş-Tüccar
    • Çiler Özenir
    • Nazlıcan Erdoğan Gövez
    • Yesim Ozogul
    • Tuba Esatbeyoglu
    • Fatih Ozogul

  • PubMed: 41280398
  • DOI: 10.3389/fnut.2025.1678150

  5 Insights on

  • Reduced Severity of Allergic Rhinitis Symptoms

  • Low evidence

  Consumption of Lactobacillus acidophilus L-92 has been associated with alleviation of symptoms in subjects with allergic rhinitis.

  Effect

  Beneficial

  Effect size

  Moderate

• Gut Microbiota: An Immersion in Dysbiosis, Associated Pathologies, and Probiotics.

  • 2025-05-07
  • Review
  • Microorganisms 13(5)
  • • Valentina Origüela
    • Alvaro Lopez-Zaplana

  • PubMed: 40431257
  • DOI: 10.3390/microorganisms13051084

  7 Insights on

  • Reduced Severity of Allergic Rhinitis Symptoms

  • Low evidence

  Lactobacillus acidophilus L-92 has been reported to alleviate symptoms and improve quality of life in patients with allergic rhinitis.

  Effect

  Beneficial

  Effect size

  Moderate

• The Role of Probiotics in Enhancing Animal Health: Mechanisms, Benefits, and Applications in Livestock and Companion Animals.

  • 2025-10-15
  • Review
  • Animals : an open access journal from MDPI 15(20)
  • • Sorin Marian Mârza
    • Camelia Munteanu
    • Ionel Papuc
    • Lăcătuş Radu
    • Robert Cristian Purdoiu

  • PubMed: 41153915
  • DOI: 10.3390/ani15202986

  4 Insights on

  • Reduced Severity of Allergic Rhinitis Symptoms

  • Low evidence

  Probiotics, including Lactobacillus acidophilus L-92, have been reported to improve symptoms of allergic rhinitis and other allergic diseases in clinical studies.

  Effect

  Beneficial

  Effect size

  Moderate

• Efficacy of Lactobacillus and Bifidobacterium in Allergic Rhinitis: A Narrative Review.

  • 2025-07-10
  • Review
  • Cureus 17(7)
  • • Tejaswi Mishra
    • Ksbs Krishna Sasanka
    • Sree Sudha Ty
    • Gulistan Bano
    • Swaha Panda
    • M Mohan Raj
    • Himel Mondal
    • Pradosh Kumar Sarangi

  • PubMed: 40786436
  • DOI: 10.7759/cureus.87644

  4 Insights on

  • Reduced Severity of Allergic Rhinitis Symptoms

  • Low evidence

  Clinical data, though heterogeneous, suggest that selected strains may improve nasal symptoms and quality of life in both adult and pediatric populations.

  Effect

  Beneficial

  Effect size

  Moderate