Lactobacillus acidophilus MAK32L61A and Improved Immune Response 3 of 3 papers Population: All (3) Unspecified (2) Clinical (1)
2022-08-03 Clinical Trial Food & Function 13(15) L. Xue Zongqi Li Jiabao Xue Huiting Wang Tao Wu R. Liu Wenjie Sui M. Zhang Low evidence Animal Study Clinical And it could enhance the immune response of the body through the TLR4/NF-κB signaling pathway.
Effect Beneficial Effect size Large 2021-09 RCT · n = 360 Poultry Science 100(9) Zhengke Wu Kexin Yang A. Zhang Wenhuan Chang A. Zheng Zhi-Min Chen Huiyi Cai Guohua Liu Low evidence Rigorous Journal Animal Study L. acidophilus supplementation reduced the serum CRP, DAO, and LPS levels at 14 d and 21 d; upregulated the mRNA expression of occludin and ZO-1 in the jejunum and ileum, and downregulated the mRNA expression of iNOS, IL-8, and IL-1β in the jejunum in E. coli challenged birds at 21 d (P < 0.05).
Effect Beneficial Effect size Moderate Significant Yes 2020-03-30 RCT · n = 240 Fish Physiology and Biochemistry 46(4) I. Adeshina M. I. Abubakar Bunmi Elizabeth Ajala Transforming growth factor beta (TGFβ), interleukin 8 (IL-8), and tumor necrosis factor alpha (TNF-alpha) were significantly stimulated.
Effect Beneficial Effect size Large Significant Yes