Lactobacillus acidophilus MAK32L61A and Reduced Serum Total Cholesterol Levels

• Effect of Lactobacillus acidophilus NS1 on plasma cholesterol levels in diet-induced obese mice.

  • 2015-03
  • Clinical Trial
  • Journal of Dairy Science 98(3)
  • • M. Song
    • S. Park
    • H. Lee
    • B. Min
    • S. Jung
    • S. Park
    • E. Kim
    • S. Oh

  • PubMed: 25468703
  • DOI: 10.3168/jds.2014-8586

  5 Insights on

  • Reduced Serum Total Cholesterol Levels

  • Low evidence
  • Rigorous Journal
  • Animal Study

  Total cholesterol and low-density lipoprotein (LDL) cholesterol levels were significantly lower in mice fed an HFD with L. acidophilus NS1 than in those fed an HFD only.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

• The hypocholesterolaemic effects of Lactobacillus acidophilus American Type Culture Collection 4356 in rats are mediated by the down-regulation of Niemann-Pick C1-Like 1

  • 2010-05-05
  • Clinical Trial
  • British Journal of Nutrition 104(6)
  • • Ying Huang
    • Jinfeng Wang
    • Yi Cheng
    • Yong-chen Zheng

  • PubMed: 20441669
  • DOI: 10.1017/S0007114510001285

  5 Insights on

  • Reduced Serum Total Cholesterol Levels

  • Low evidence
  • Animal Study

  L. acidophilus 4356 feeding significantly lowered total serum cholesterol.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

• Assimilation of cholesterol by Lactobacillus acidophilus

  • 1985-02
  • Clinical Trial
  • Applied and Environmental Microbiology 49(2)
  • • S. Gilliland
    • C. R. Nelson
    • C. Maxwell

  • PubMed: 3920964
  • DOI: 10.1128/aem.49.2.377-381.1985

  2 Insights on

  • Reduced Serum Total Cholesterol Levels

  • Low evidence
  • Highly Cited
  • Animal Study
  • Clinical

  Consumption of L. acidophilus RP32, which was selected for its ability to grow well in the presence of bile and to assimilate cholesterol from the laboratory medium, significantly inhibited increases in serum cholesterol levels of pigs (P less than 0.05) fed a high-cholesterol diet.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes