A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial.
- 2020-05
- RCT · n = 80
- Digestive and Liver Disease 52(5)
- S. Sadrin
- S. Sennoune
- B. Gout
- S. Marque
- J. Moreau
- Karim Zinoune
- J. Grillasca
- O. Pons
- J. Maixent
- PubMed: 31952938
- DOI: 10.1016/j.dld.2019.12.009
- High evidence
- Clinical
Abdominal pain score was significantly improved in both groups at weeks 4 and 8 (P < 0.0001), but no significant differences were found between groups at week 8 (19.0 ± 2.5 vs 25.1 ± 2.6, respectively; LS Means differences = 6.0 ± 3.2; P = 0.06).
- Effect
- Neutral
- Effect size
- Small
- Significant
- No