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Evidence-Based Supplement Research
Evidence-Based Supplement Research
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Lactobacillus amylovorus and Improved Intestinal Barrier Function

Research synthesisLow evidenceModerate effect3 studies · 3 beneficial · 0 neutral · 0 harmful

Across 3 studies, all reported beneficial moderate-sized effects of Lactobacillus amylovorus on intestinal barrier function. Two of the three studies achieved statistical significance, and the evidence is derived primarily from animal models (piglets, sows, and lambs). No consistent dose range or study duration was reported across studies.

  • Studied populations: newborn piglets with intrauterine growth restriction, pregnant sows infected with Clostridium perfringens type A, weaned lambs

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). All studies were conducted in animal populations, and generalizability to humans is uncertain. Doses and study forms were not reported, limiting practical application.

Generated Jun 11, 2026
5 of 5 papers
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