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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Lactobacillus amylovorus and Improved Intestinal Barrier Function

Research synthesisLow evidenceModerate effect3 studies · 3 beneficial · 0 neutral · 0 harmful

Across 3 studies, all reported beneficial moderate-sized effects on intestinal barrier function, with 2 of 3 reaching statistical significance. The evidence is limited to animal models (piglets, sows, lambs) and includes studies where L. amylovorus was not the sole intervention, making the specific effect uncertain. No consistent dose or duration data were available.

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Additionally, two of the three studies involved other interventions (Bacillus subtilis, epigallocatechin) rather than L. amylovorus alone, so the specific effect of L. amylovorus is uncertain. All studies were in animal models; human data are lacking.

Generated Jul 12, 2026
5 of 5 papers
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