Lactobacillus brevis SBC8803 and Increased Appetite

• Oral administration of heat-killed Lactobacillus brevis SBC8803 elevates the ratio of acyl/des-acyl ghrelin in blood and increases short-term food intake.

  • 2019-07-10
  • Beneficial microbes 10(6)
  • • H Saito
    • Y Nakakita
    • S Segawa
    • Y Tsuchiya

  • PubMed: 31190555
  • DOI: 10.3920/bm2018.0091

  3 Insights on

  • Increased Appetite

  • Low evidence
  • Rigorous Journal
  • Animal Study

  oral administration of 500 mg/kg hk-SBC8803 to rats tended to upregulate acyl ghrelin concentration ... and significantly increased the ratio of acyl to des-acyl (inactive) ghrelin ... which corresponded to a tendency of stimulating food intake ... at 30 min post-treatment

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

• Effects of intraduodenal injection of Lactobacillus brevis SBC8803 on autonomic neurotransmission and appetite in rodents

  • 2013-02
  • Clinical Trial
  • Neuroscience Letters 539
  • • Y. Horii
    • Y. Nakakita
    • Y. Fujisaki
    • Saori Yamamoto
    • Nanako Itoh
    • K. Miyazaki
    • H. Kaneda
    • K. Oishi
    • T. Shigyo
    • K. Nagai

  • PubMed: 23391754
  • DOI: 10.1016/j.neulet.2013.01.037

  3 Insights on

  • Increased Appetite

  • Low evidence
  • Animal Study
  • Clinical

  We observed that administration of SBC8803 elevated food intake... these findings suggest that heat-killed SBC8803 enhances appetite by elevating digestion and absorption abilities via changes in autonomic neurotransmission

  Effect

  Beneficial

  Effect size

  Moderate