Research synthesisLow evidenceModerate effect5 studies · 5 beneficial · 0 neutral · 0 harmful
Across 5 studies, all reported beneficial effects with predominantly moderate effect sizes. The only randomized controlled trial (RCT) found a significant moderate effect on reducing exercise-induced inflammation in healthy adults after 6 weeks of administration. However, the remaining 4 studies are reviews that provide indirect mechanistic support rather than direct clinical evidence from interventions with Lactobacillus brevis SBC8803.
- Studied populations: healthy adults (from the single RCT); other populations (e.g., people with IBD) mentioned only in reviews, with no direct intervention data.
Caveats: Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Many of the included studies did not reach statistical significance — only 1 of 5 studies reported a significant finding. Additionally, the studies primarily involve other Lactobacillus strains (e.g., TWK10, paracasei) — applicability of these findings to Lactobacillus brevis SBC8803 specifically is uncertain. The evidence base is small (5 studies) and mostly consists of reviews, making conclusions preliminary.
Generated Jun 11, 2026