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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Lactobacillus casei PXN 37 and Reduced Inflammation

Research synthesisLow evidenceModerate effect3 studies · 3 beneficial · 0 neutral · 0 harmful

Across 3 studies, all reported beneficial effects of Lactobacillus casei PXN 37 on reducing inflammation, with moderate effect sizes in 2 studies and a small effect in 1. The evidence draws from meta-analyses in autoimmune and depression populations, but the evidence base is small. Doses and study durations were not consistently reported.

  • Studied populations: patients with autoimmune diseases, depressed patients with somatic comorbidities, patients with neurodegenerative diseases (Alzheimer's, Parkinson's, multiple sclerosis, mild cognitive impairment)

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed).

Generated Jun 11, 2026
3 of 3 papers
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