A synbiotic composed of Lactobacillus fermentum CECT5716 and FOS prevents the development of fatty acid liver and glycemic alterations in rats fed a high fructose diet associated with changes in the microbiota.
- 2017-06-08
- Clinical Trial
- Molecular Nutrition & Food Research 61(8)
- Belén Rivero-Gutiérrez
- Reyes Gámez-Belmonte
- M. D. Suárez
- J. Lavín
- A. Aransay
- M. Olivares
- O. Martínez-Augustin
- F. Sánchez de Medina
- A. Zarzuelo
- PubMed: 28463404
- DOI: 10.1002/mnfr.201600622
- Low evidence
- Animal Study
Treatment with the synbiotic prevented some of the pathological effects, so that treated rats did not develop steatosis or systemic inflammation, while dysbiosis and barrier function were greatly ameliorated.
- Effect
- Beneficial
- Effect size
- Moderate