Lactobacillus gasseri and Reduced Inflammation

• Lactobacillus gasseri CBT LGA2 alleviates muscle protein degradation and inflammation in immobilization-induced mouse.

  • 2026-01-07
  • Frontiers in microbiology 16
  • • Ji Hun Jang
    • So Jeong Lim
    • Hyo Su Choi
    • Sanghyun Lim
    • Nam Su Oh

  • PubMed: 41574345
  • DOI: 10.3389/fmicb.2025.1728172

  1 Insight on

  • Reduced Inflammation

  • Low evidence

  Additionally, LGA2 lowered TNF-α, IL-6, iNOS, and COX-2 levels while restoring IL-10 in muscle and serum.

  Effect

  Beneficial

  Effect size

  Moderate

• Lactobacillus gasseri-derived postbiotics promote osteogenic differentiation in BMSCs via ameliorating mitochondrial oxidative stress.

  • 2026-01
  • Biochemical and biophysical research communications 795
  • • Ziwei Guo
    • Yun Yuan
    • Keyu Lu
    • Shi Yin
    • Wei Bi

  • PubMed: 41389616
  • DOI: 10.1016/j.bbrc.2025.153113

  3 Insights on

  • Reduced Inflammation

  • Low evidence
  • Animal Study

  In vivo, postbiotic treatment significantly enhanced bone regeneration and reduced local inflammation in calvarial defects.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes