Research synthesisModerate evidenceMixed effect size4 studies · 4 beneficial · 0 neutral · 0 harmful
Across 4 studies (including one meta-analysis and one small RCT), all reported beneficial effects of Lactobacillus jensenii LBV 116 on vaginal microbiota, with one meta-analysis showing a statistically significant moderate reduction in Nugent score. The predominant effect size is mixed (small to moderate), and the evidence primarily comes from clinical populations with vaginal dysbiosis, such as postmenopausal breast cancer patients, women with bacterial vaginosis, and pregnant women with herpes infection. No dose or duration data were consistently reported.
- Studied populations: Women with vaginal dysbiosis, including postmenopausal breast cancer patients, pregnant women with herpes infection, and women with bacterial vaginosis.
Caveats: Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Evidence base is small (only 4 studies) — conclusions should be considered preliminary. Many of the included studies did not reach statistical significance — effect may be smaller than the predominant direction suggests. Study durations and doses were not consistently reported, limiting comparability across studies.
Generated Jul 11, 2026